Vitamin D suppresses inflammatory responses in insulin resistance
نویسندگان
چکیده
منابع مشابه
Role of Vitamin D in Insulin Resistance
Vitamin D is characterized as a regulator of homeostasis of bone and mineral metabolism, but it can also provide nonskeletal actions because vitamin D receptors have been found in various tissues including the brain, prostate, breast, colon, pancreas, and immune cells. Bone metabolism, modulation of the immune response, and regulation of cell proliferation and differentiation are all biological...
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Objective(s): The aim of this study was to investigate the effect of vitamin D on glucose metabolism, as well as the expression of five key genes involved in the development of diabetes complications in liver tissue of diabetic rats. Materials and Methods: Twenty-four male Sprague–Dawley rats were randomly divided into three groups (8 ra...
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Background and Aim: The aim of this study was to investigate the effects of vitamin D supplementation during progressive resistance training on insulin resistance, blood lipids and body fat percentage in T2D men with vitamin D deficiency. Methods: Forty-eight men with T2D participated in the study voluntarily and were randomly assigned to 4 groups (n=12) including, resistance training (RT), vi...
متن کاملDecreased Anti-Inflammatory Responses to Vitamin D in Neonatal Neutrophils
Neutrophil activity is prolonged in newborns, suggesting decreased exposure and/or responses to immunosuppressive modulators, such as 1,25-hydroxyvitamin D(3) (1,25-vit D(3)). We hypothesized that 1,25-vit D(3) suppresses neutrophil activation and that this response is impaired in newborns. Consistent with this, 1,25-vit D(3) decreased LPS-induced expression of macrophage inflammatory protein-1...
متن کاملSerum vitamin-D predicts insulin resistance in individuals with prediabetes
BACKGROUND & OBJECTIVES Patients with diabetes and vitamin-D insufficiency have increased insulin resistance. Similar observations among individuals with prediabetes are not well documented. The aim of this study was to find the occurrence of vitamin-D insufficiency/deficiency among individuals with prediabetes and to evaluate the relationship between vitamin-D status and insulin resistance. ...
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ژورنال
عنوان ژورنال: Journal of thee Medical Sciences (Berkala Ilmu Kedokteran)
سال: 2020
ISSN: 0126-1312,2356-3931
DOI: 10.19106/jmedsci005202202009